Short-term prophylaxis (STP) with plasma derived human C1 inhibitor concentrate (pdhC1-INH) in two pregnant women with hereditary angioedema (HAE): an experience in Rio de Janeiro – Brazil

نویسندگان

  • Solange Oliveira Rodrigues Valle
  • Maria Luiza Oliva Alonso
  • Sérgio Duarte Dortas
  • Soloni Afra Pires Levy
  • Ana Paula Ferracciú Coutinho Millet
  • Alfeu Tavares França
  • Alfeu Tavares França
  • Ana Luiza Ribeiro Bard De Carvalho
چکیده

Short-term prophylaxis (STP) with plasma derived human C1 inhibitor concentrate (pdhC1-INH) in two pregnant women with hereditary angioedema (HAE): an experience in Rio de Janeiro – Brazil Solange Oliveira Rodrigues Valle, Maria Luiza Oliva Alonso, Sérgio Duarte Dortas Junior, Soloni Afra Pires Levy, Ana Paula Ferracciú Coutinho Millet, Alfeu Tavares França, Alfeu Tavares França, Ana Luiza Ribeiro Bard De Carvalho

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Risk of laryngeal edema and facial swellings after tooth extraction in patients with hereditary angioedema with and without prophylaxis with C1 inhibitor concentrate: a retrospective study.

OBJECTIVE Tooth extractions may trigger clinical symptoms of hereditary angioedema due to C1 inhibitor deficiency (HAE-C1-INH). The aim of this study was to determine how many tooth extractions were followed by symptoms of HAE-C1-INH in patients with and without preoperative short-term prophylaxis with C1 inhibitor concentrate. STUDY DESIGN Tooth extractions and clinical symptoms of HAE-C1-IN...

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BACKGROUND Hereditary Angioedema (HAE) is a rare autosomal dominant condition characterized by episodic angioedema, which may be triggered by invasive procedures and surgery. C1 inhibitor (C1 INH) was approved in the United States and Canada in 2009 and 2010, respectively, for the treatment of acute attacks. Most recently in April 2013, it was approved in Europe for short-term prophylaxis (STP)...

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Self-administered C1 esterase inhibitor concentrates for the management of hereditary angioedema: usability and patient acceptance

Hereditary angioedema (HAE) is a rare genetic disease characterized by episodic subcutaneous or submucosal swelling. The primary cause for the most common form of HAE is a deficiency in functional C1 esterase inhibitor (C1-INH). The swelling caused by HAE can be painful, disfiguring, and life-threatening. It reduces daily function and compromises the quality of life of affected individuals and ...

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Short-term prophylaxis in hereditary angioedema due to deficiency of the C1-inhibitor--a long-term survey.

BACKGROUND Hereditary angioedema is a potentially life-threatening disorder, because edema occurring in the mucosa of the upper airways can lead to suffocation. The management of HAE consists of avoiding the triggering factors, prophylaxis, and the acute treatment of edematous episodes. Medical procedures can also provoke edematous attacks, and therefore, short-term prophylaxis (STP) is recomme...

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Recombinant Human C1 Esterase Inhibitor in the Management of Hereditary Angioedema

Hereditary angioedema (HAE), a rare autosomal dominant genetic disorder, is caused by a deficiency in functional C1 esterase inhibitor (C1-INH). This potentially life-threatening condition manifests as recurrent attacks of subcutaneous and submucosal swelling of the skin, gastrointestinal tract and larynx. The management of HAE includes treatment of acute episodes, short-term prophylaxis in pre...

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عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2015